https://doi.org/10.4081/amsa.2023.8
Esophageal manometry: a valuable tool for the comprehensive management of COVID-19-related hypoxic respiratory failure
Submitted: 3 March 2023
Accepted: 11 March 2023
Published: 6 April 2023
Accepted: 11 March 2023
Abstract Views: 363
PDF: 147
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
The optimal management of respiratory failure related to SARS-CoV-2 infection is a subject of heated debates in the scientific community. The lack of solid scientific evidence, combined with the unclear pathophysiology of COVID-19 pneumonia, means that the modalities and duration of ventilator assistance often rely on subjective assessments of the doctor on call. In establishing a suitable respiratory support, it is essential to evaluate the degree of activation of the respiratory muscles as objectively as possible. Among the various methods of evaluating the inspiratory effort, measurement of the phasic variations of esophageal pressure (intended as a surrogate of pleural pressure) represents the gold standard. Esophageal pressure measurement can be implemented in a minimally invasive way in every patient category, does not require sophisticated devices, and provides objective data about respiratory muscle activity. In patients with ongoing COVID-19-related respiratory failure, esophageal pressure monitoring allows i) optimizing the type and settings of noninvasive ventilation, ii) providing objective support in the delicate choice of establishing invasive ventilation in cases in which such an indication is unclear, and iii) monitoring the clinical evolution of COVID-19 pneumonia to allow early interception of cases with progressive worsening of lung function. Esophageal manometry provides a complete and objective assessment of respiratory muscle activity. Its clinical use in patients with respiratory failure in the course of COVID-19 would allow clarifying some pathophysiological aspects of the disease and customizing ventilatory support according to the needs of specific patients.
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How to Cite
Viola, L., Bolondi, G., Bergamini, C., Bissoni, L., Benni, M., Santonastaso, D. P., … Circelli, A. (2023). Esophageal manometry: a valuable tool for the comprehensive management of COVID-19-related hypoxic respiratory failure. Advances in Anesthesia and Pain Medicine, 1(1). https://doi.org/10.4081/amsa.2023.8
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